DOS Games made for DOS require an emulator to run on Windows. Use DOSBox or a frontend like D-Fend Reloaded and read this guide to play DOS games on your Windows PC.
Zero Magazine issue 4 (1990) - "The worst thing is the difficulty. It took me ages to get through the wormhole thing and when I did do it, the Enterprise was so smashed up it was naff all use for anything. Perhaps extreme perseverance is what's needed. Despite reservations about the way it's put together. I'm pretty impressed. Star Trek V in visually ace and, if you're prepared to sick with it, entertaining. All it needs is a digitised "psshhqueak" when you enter the bridge, to make it perfect."
These are some of the abandoned games similar to Star Trek V: The Final Frontier in some way.
Frontier: First Encounters
Descent: FreeSpace - The Great War
Starglider 2
Starglider