Leisure Suit Larry 1: In the Land of the Lounge Lizards

A bizarre, unfounded hoax at the time was that the player's computer would catch a computer virus if Larry had unprotected sex with one of the NPCs; in actuality, if Larry has sex in the game with a prostitute without using a condom, he contracts a particularly virulent sexually transmitted infection, his genitals explode and he commits suicide.

There is a controversial joke early on in the game, where the player
has the ability to try to get Larry to flirt with the male patrons in
the bar, only to cause the offended patron to kill Larry.

A running joke is the appearance of a black dog that will pee on Larry (perhaps mistaking him for a fire hydrant) when he stands immobile for some time. The dog also appears briefly in the sequel. However when you eat the pills of spanish fly when the dog is in sight, you end up in jail.