To launch the game, run Rampage/Rampage.exe.
DOS Games made for DOS require an emulator to run on Windows. Use DOSBox or a frontend like D-Fend Reloaded and read this guide to play DOS games on your Windows PC.
"As a kid, I remember spending hours at the bar down the road playing at Rampage as Lizzie. Destroying buildings and eating tasty humans was one of my favourite past-times. It's surprising that the coin-op conversion of Rampage for DOS ended up as a nice game. Granted it's not the arcade, Rampage for DOS retains a lot of the appeal of the coin-op." - Abandonware DOS