Games set in space

Science fiction doesn't always means space battles, space exploration, exploding stars, etc. In some games, though, the "space" element is heavily present. Space simulations, shoot 'em ups, RPGs are some of the genres where science fiction "space" games are abundant.

Most popular space games

Space Quest 1: The Sarien Encounter

adventureDOS, Mac

Master of Orion 2: Battle at Antares

strategyDOS, Windows XP/98/95

Wing Commander

vehicle simulationDOS

Space games

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Anacreon: Reconstruction 4021

DOS1987freeware3.9/5 Thinking Machine Associates

Anacreon: Reconstruction 4021 is one of the first 4x turn-based strategy games, ASCII based. Anacreon is set in space, as most 4x sci-fi games are, and was published by Thinking Machines Associates and designed by George Moromisato who later re-released the game as freeware.
Ascendancy

DOS19954.1/5 The Logic Factory

Ascendancy is a science fiction themed turn-based strategy game developed by The Logic Factory and released in 1995 for DOS. Ascendancy is a classic 4X game (eXpand, eXplore, eXploit, eXterminate), similar to Master of Orion, yet with a few differences such as a technology tree.
Ascii Sector

Windows XP/98/95LinuxDOS2007freeware4/5
Astro Dodge

DOS19823.6/5 Digital Marketing Corporation
Babylon 5: I've Found Her

Windows XP/98/952003freeware3.8/5 Space Dream Factory
Battlestar

Windows 3.x1996freeware3.6/5
Blasteroids

DOS19893.8/5 Atari
Captain Blood

DOSMac19883.8/5 ERE Informatique

Exxos released Captain Blood for PC, Amiga and Atari ST in 1988. Captain Blood is a peculiar science fiction game developed by french ERE Informatique which defies genres: it's part adventure, part space exploration, part simulation.
CHAMP Asteroids

DOS1997remake4/5 ChamProgramming corp.
Command Adventures: Starship

DOS19953.5/5 Future Vision
Cosmic Crusader

DOS19823.8/5 Funatics Software
Deep space: Operation Copernicus

DOS19863.9/5 Lerner Research
Descent: FreeSpace - The Great War

Windows XP/98/951998protected3.9/5 Volition
Devastator

DOS19843.4/5 COMPUTE! Publications
Eagle's Rider

DOS19914.1/5 Microids
Earthrise

DOS19903.3/5 Interstel Corporation
EGA Trek

DOS1988remake2.7/5
EGA-Roids

DOS1986freewareremake3.7/5 Designer Software
Elite

DOS1987freeware4.1/5 Firebird
Elite Plus

DOS1991freeware4.1/5 Realtime Games
Epic

DOS1992protected3.9/5 Digital Image Design
Eye of the Storm

DOS19932.4/5 Rebellion Developments
Frederik Pohl's Gateway

DOS19924.1/5 Legend Entertainment

Frederik Pohl's Gateway is one of the best abandoned adventures games from Legend Entertainment. Gateway is an interactive fiction with graphics and an improved interface (unusual for IFs), based on the Frederik Pohl's novel Gateway. Tt was designed by Michael Verdu and Glen R. Dahlgren and published by Legend Entertainment in 1992.
Frontier: Elite 2

DOS19934.2/5 Frontier Developments
Frontier: First Encounters

DOS19954.1/5 Frontier Developments
Galaxian

DOS19834/5 Namco
Galaxy

DOS19814/5 Microcomputer Games Inc.
Gamma Force in Pit of a Thousand Screams

DOS19883.8/5 Tom Snyder Productions
Gateway 2: Homeworld

DOS1993protected4/5 Legend Entertainment
Hard Nova

DOS19903.7/5 Malibu Interactive